EBHC Library > Methodology of Research > Clinical Research > Low Quality

Page last update: 29/09/2012

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• General
  • Gogol M. Cochrane reviews v industry supported meta-analyses: ten questions to assess bias in medical research. BMJ 2006;333:916-7.
  • Berger VW, Ioannidis JP. The Decameron of poor research. BMJ 2004;329:1436-40.
  • The scandal of poor epidemiological research
  • Altman DG. Poor-quality medical research. What can journals do?  JAMA 2002;287:2765-2767
  • Rennie D. Fair conduct and fair reporting of clinical trials. JAMA 1999;282:1766-8.
  • Knottnerus JA, Geert JD. Medicine based evidence, a prerequisite for  evidence based medicine. BMJ 1997;315:1109-10
  • Huston P, Moher D. Redundancy, disaggregation, and the integrity of medical research. Lancet 1996;347:1024-6
  • Smith R. Where is the wisdom...? The poverty of medical evidence. BMJ 1991;303:798-799.
  • Altman DJ. The scandal of poor medical research. BMJ 1994;308:283-4.
• Gray zones
  • Naylor CD. Grey zones of clinical practice: some limits to evidence-based medicine. Lancet 1995;345:840-2
• Integrity
  • Korn D, Ehringhaus S. Principles for strengthening the integrity of clinical research. PLoS Clin Trials 2006;1:e1

  • [No authors listed]. The next step: ensuring integrity of scientific research. Lancet 2002;360:499

• Diseases Mongering

  • Mintzes B. Disease mongering in drug promotion: do governments have a regulatory role? PLoS Med 2006;3:e198.

  • Moynihan R, Henry D. The fight against disease mongering: generating knowledge for action. PLoS Med 2006;3:e191.

  • Tiefer L. Female sexual dysfunction: a case study of disease mongering and activist resistance. PLoS Med 2006;3:e178.

  • Heath I. Combating disease mongering: daunting but nonetheless essential. PLoS Med 2006;3:e146

  • Moynihan R, Heath I, Henry D. Selling sickness: the pharmaceutical industry and disease mongering. BMJ 2002;324:886-91

• DUET- Database of Uncertainties about the Effects of Treatments. A resource to help prioritise new research