EBHC Library > Bibliographic resources > Series of Articles > Randomized Controlled Trials

Page last update: 29/09/2012

 
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Treating individuals
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Summerskill W. Evidence-based practice and the individual. Lancet 2005;365:13-4

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Rothwell PM. 1. External validity of randomised controlled trials: "to whom do the results of this trial apply?". Lancet 2005;365:82-93

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Rothwell PM. 2. Subgroup analysis in randomised controlled trials: importance, indications, and interpretation. Lancet 2005;365:176-86

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Rothwell PM, Mehta Z, Howard SC, et al. 3. From subgroups to individuals: general principles and the example of carotid endarterectomy. Lancet 2005;365:256-65

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Thompson SG, Higgins JP. 4. Can meta-analysis help target interventions at individuals most likely to benefit? Lancet 2005;365:341-6

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Jackson R, Lawes CM, Bennett DA, et al. Treatment with drugs to lower blood pressure and blood cholesterol based on an individual's absolute cardiovascular risk. Lancet 2005;365:434-41

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Trials on trial
punto elenco Van Der Weyden MB. Trials on trial. Med J Aust  2001;175:241
punto elenco Gebski VJ, Beller EM, Keech AC. Randomised controlled trials: elements of a good study. Med J Aust 2001;175:272-274
punto elenco Ghersi D, Gebski VJ, Keech AC. Scientific background and rationale for a randomised controlled trial. Med J Aust 2001;175:386
punto elenco Keech AC, Gebski VJ. Selecting participants for clinical trials. Med J Aust 2001;175:490-1
punto elenco Brighton JK, Gebski VJ, Keech AC. Specifying interventions in a clinical trial.MJA 2002;176:281-282
punto elenco Kirby A, Gebski VJ Keech AC. Determining the sample size in a clinical trial. Med J Aust 2002;177:256-257
punto elenco Keech AC, Gebski V. Managing the resource demands of a large sample size in clinical trials: can you succeed with fewer subjects? Med J Aust 2002;177:445-7
punto elenco Gebski V, Marschner I, Keech AC. Specifying objectives and outcomes for clinical trials Med J Aust 2002;176:491-492
punto elenco Gebski VJ, Beller EM, Keech AC. Randomisation in clinical trials. Med J Aust 2002;177:565-567
punto elenco Gebski VJ, Beller EM, Keech AC. Statistical methods in clinical trials. Med J Aust 2003;178:182-184
punto elenco Cakir B, Gebski VJ, Keech AC. Flow of participants in randomised studies. MJA 2003;178:348-349
punto elenco Hague WE, Gebski VJ, Keech AC. Recruitment to randomised studies. Med J Aust 2003;178:579-581
punto elenco Burgess DC, Gebski VJ, Keech AC. Baseline data in clinical trials. MJA 2003;179:105-107
punto elenco Heritier SR, Gebski VJ, Keech AC. Inclusion of patients in clinical trial analysis: the intention-to-treat principle. Med J Aust 2003;179:438-40
punto elenco O'Connell RL, Gebski VJ, Keech AC. Making sense of trial results: outcomes and estimation. Med J Aust 2004;180:128-30.
punto elenco Cook DI, Gebski VJ, Keech AC. Subgroup analysis in clinical trials. Med J Aust 2004;180:289-291
punto elenco Simes RJ, Gebski VJ, Keech AC. Subgroup analysis: application to individual patient decisions. Med J Aust 2004;180:467-9
punto elenco Keech AC, Wonders SM, Cook DI, Gebski VJ. Balancing the outcomes: reporting adverse events. Med J Aust 2004;181:215-8
punto elenco Lord SJ, Gebski VJ, Keech AC. Multiple analyses in clinical trials: sound science or data dredging? Med J Aust 2004;181:452-4
punto elenco Seale JP, Gebski VJ, Keech AC. Generalising the results of trials to clinical practice. Med J Aust 2004;181:558-60
punto elenco Forder PM, Gebski VJ, Keech AC. Allocation concealment and blinding: when ignorance is bliss. Med J Aust 2005;182:87-9
punto elenco Wilcken NR, Gebski VJ, Pike R, et al. Putting results of a clinical trial into perspective. MJA 2007;186:368-370.
punto elenco Keech AC, Pike R, Granger RE, et al. Interpreting the results of a clinical trial. MJA 2007;186):318-319

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Reliable assessment of the effects of treatment on mortality and major morbidity
punto elenco Collins R, McMahon S. I: Clinical Trials. Lancet 2001;357:373-80
punto elenco McMahon S, Collins R. II: Observational Studies. Lancet 2001;357:455-62.

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punto elenco Placebo-controlled trials and active-control trials in the evaluation of new treatments
punto elenco Simon R. Are placebo-controlled clinical trials ethical or needed when alternative treatment exists? Ann Intern Med 2000;133:474-5.
punto elenco Temple R, Ellenberg SS. Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 1: ethical and scientific issues. Ann Intern Med 2000;133:455-63.
punto elenco Ellenberg SS, Temple R. Placebo-controlled trials and active-control trials in the evaluation of new treatments. Part 2: practical issues and specific cases. Ann Intern Med 2000;133:464-70.
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Why randomized controlled trials fail but needn't
punto elenco Sackett DL, Hoey  J. Why randomized controlled trials fail but needn't: a new series is launched [editorial]. CMAJ 2000;162:1301-2
punto elenco Sackett DL. Failure to gain "coal-face" commitment and to use the uncertainty principle. CMAJ 2000;162:1311-4
punto elenco Sackett DL. Failure to employ physiological statistics, or the only formula a clinician-trialist is ever likely to need (or understand!) CMAJ 2001;165:1226-37.

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Understanding controlled trials
punto elenco Sibbald B, Roland M. Why are randomized controlled trials important? BMJ 1998;316:201
punto elenco Roland M, Torgerson DJ.  What are pragmatic trials? BMJ 1998;316:285
punto elenco Torgerson DJ, Sibbald B. What is a patient preference trial? BMJ 1998;316:360
punto elenco Torgerson DJ, Roland M. What is Zelen's design? BMJ 1998;316:606
punto elenco Sibbald B, Roberts C. Crossover trials. BMJ 1998;316:1719-20
punto elenco Roberts C, Sibbald B. Randomising groups of patients BMJ 1998;316:1898
punto elenco Roland M, Torgerson D. What outcomes should be measured? BMJ 1998;317:1075
punto elenco Roberts C, Torgerson D. Randomisation methods in controlled trials.BMJ 1998;317:1301
punto elenco Roberts C, Torgerson D. Baseline imbalance in randomised controlled trials.BMJ 1999;319:185
punto elenco Roberts C, Torgerson D. Randomisation methods: concealment. BMJ 1999;319:375-6

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